At this time, officials believe a northbound vehicle collided with a westbound vehicle, but it is unclear exactly how the accident occurred.
Clay County Sheriff Mike Heaton said an accident reconstruction would be performed to help determine the official cause of incident, which could take a couple of weeks to complete.
Officials confirmed that one victim sustained minor injuries, one was taken by air ambulance to an Indianapolis hospital and Clay County Coroner Rick Swearingen pronounced the third victim dead at the scene.
Heaton said that no information about the victims would be released until official notification of the three victim's families.
Members of the Brazil City Police, Dick Johnson and Posey Township Volunteer Fire Departments and the Clay County Search and Rescue provided assistance at the accident scene.
The Brazil Times will provide updates about this story as they become available.