By The Associated Press
PHILADELPHIA -- Jesus Colome walked Jayson Werth to force in the winning run in the bottom of the 10th inning, giving the Philadelphia Phillies an 8-7 victory over the Washington Nationals on Thursday.
The defending NL East champions overcame a 5-0, first-inning deficit to avoid opening the season with a three-game sweep at home for the third straight year.
Jimmy Rollins reached on an infield single to start the bottom of the 10th against Colome (0-1). The reigning NL MVP never hesitated rounding second base and advanced all the way to third on Shane Victorino's perfect sacrifice.
After Chase Utley and Ryan Howard were intentionally walked to load the bases, Werth walked on four pitches to end it.
Clay Condrey (1-0), the seventh pitcher used by Philadelphia, tossed a perfect 10th.
Trailing 6-1 in the sixth, the Fightin' Phils rallied with seven straight singles to tie it and took a 7-6 lead on their eighth single of the inning.
Padres 3, Astros 2
SAN DIEGO (AP) -- Trevor Hoffman kept up his seesaw season when he earned the save in San Diego's victory over Houston.
Hoffman pitched a perfect ninth less than 24 hours after blowing the save and taking the loss by giving up four runs in the ninth inning of a 9-6 defeat, including Lance Berkman's two-out, three-run homer.
It was Hoffman's second save in three chances, extending his big league record to 526.
Hoffman earned a save Tuesday night after blowing chances in the final three games last year, including a 13-inning loss at Colorado in the wild-card tiebreaker game on Oct. 1.
Enrique Gonzalez (1-0) got the win and Kevin Kouzmanoff hit a two-run homer for the Padres, who took three of four from the Astros in the opening series.
Oscar Villarreal (0-1) was charged with the loss.
Cubs 6, Brewers 3
CHICAGO (AP) -- Former closer Ryan Dempster was a winner in his return to the rotation, Aramis Ramirez homered and Alfonso Soriano had two RBIs for the Cubs.
Moved back to the leadoff spot after hitting second the first two games, Soriano drew a bases-loaded walk in the fourth to force in the go-ahead run and added an RBI single in the sixth to snap a season-starting 0-for-11 slump.
Starter-turned-closer Kerry Wood pitched the ninth for his first career save as Chicago averted an opening three-game sweep.
Dempster (1-0) made his first start since May 4, 2005 -- when he was in his second season with the Cubs, began the year in the rotation and then became the closer.
Dave Bush (0-1) allowed six runs and six hits in 5 1-3 innings and Prince Fielder had two RBIs for Milwaukee.
Reds 3, Diamondbacks 2
CINCINNATI (AP) -- Johnny Cueto allowed nothing more than Justin Upton's solo homer in seven innings, striking out 10 in an overpowering debut for Cincinnati.
Pitching in a steady rain, the 22-year-old right-hander struck out eight of his first 13 batters. His 10 strikeouts were the most by a Reds pitcher in his big league debut since 1900, according to the Elias Sports Bureau.
Arizona's Alex Romero had a sacrifice fly in the eighth, after reliever David Weathers walked the bases loaded. Francisco Cordero pitched the ninth for his first save since the Reds gave him a $46 million, four-year deal to fix their biggest shortcoming.
Jeff Keppinger homered off left-hander Doug Davis (0-1), who failed to make it through the fourth inning of an emotional start. Davis was diagnosed with thyroid cancer last week and is to have surgery on April 10.
Cardinals 3, Rockies 0
ST. LOUIS (AP) -- Brad Thompson had a career-high six strikeouts in 6 2-3 innings to lead the Cardinals to the win.
St. Louis took two of three from the defending NL champions, who totaled five runs in the series. Colorado was 3-for-25 with runners in scoring position, two of the hits coming in the finale, but Todd Helton was thrown out at the plate in the sixth.
Thompson (1-0), a sinkerball specialist and swingman who's in the rotation while the Cardinals await several injured starters, walked two and allowed six hits. He also had his first career RBI.
Rockies starter Ubaldo Jimenez (0-1) was in trouble throughout a five-inning stint, allowing three runs and seven hits. He walked five, struck out four and threw two wild pitches.