The Panthers' big play capabilities were the biggest reasons, as Reitz scored four times on plays that went for 16 yards or more on the way to a 40-8 sectional victory.
The loss ends the Knights season at 4-6 season overall while Reitz advances to face Jasper in the second round Friday.
Things got off to a fairly good start for the Knights, who were able to force Reitz to punt following a bad snap on third down pinned the Panthers deep in their own territory.
A fumble on Reitz' next possession haulted a drive at the Knights one yard line as Northview kept the game scoreless for most of the first period.
However, the Knights weren't able to get much offensively themselves, just missing on a bomb to Zach Boetjer on the opening possession, which could have changed momentum.
Reitz got good field position after fumbling on the Knights one-yard line, getting the punt at midfield to start their first scoring drive.
The Panthers took just two players to hit paydirt as senior Ryan McIntosh hit Cuda Dimmett for a 43-yard scoring screen pass.
The Knights punted after a four-and-out on the following drive and Reitz got another big play, this time a 74-yard run from quarterback McIntosh, who squirted free down the sideline for a 13-0 lead with 10:09 left in the first half.
"We squandered some opportunities," Northview head coach George Gettle said after the game. "They got a couple of big plays that changed momentum."
Northview answered back with its best drive of the game to that point, driving down to the Panthers' 35-yard line.
Wes Sorlie carried twice for 18 yards and Trent Lancaster got free for a tough 10-yard jaunt.
The Knights reached the 35 after a pass interference call. Two shorts runs by Sorlie set the Knights up with a fourth-and-sixth situation.
The Knights called a fake punt but it was foiled as Cory Crowder slipped down on the run for a short loss.
Reitz got the final score of the half as Alordo Bell, who ran for 113 yards in the first half, scored from 16 yards out for a 19-0 lead at the break.
The Knights got the kick to open the second half but couldn't move the ball and were forced to punt back to Reitz.
The Panthers once again struck quickly. This time on a halfback pass from Jeffrey Judson to Morgan Jones, good for 32 yards.
From there, field position played a big role as Reitz scored on an 8-yard pass to Jones and got a 68-yard touchdown run from Bell.
The Knights did have the final score of the game, getting a 23-yard touchdown pass from Lancaster to Jonathan Bradshaw to cap the scoring.
"We didn't meet our expectations," Gettle said of his team's hopes for the year. "We had a lot of kids play good football. We just got bit by the injury bug a bit."
Northview 0 0 0 8 -- 8
Evansville Reitz 7 12 21 0 -- 40
Evansville Reitz -- R. McIntosh 43 pass to Dimmett (Hudson kick), 1:29
Evansville Reitz -- McIntosh 74 run (kicked failed) 10:09
Evansville Reitz -- Bell 16 run (pass failed) 3:21
Evansville Reitz -- McIntosh 32 pass to Jones (kick good) 9:39
Evansville Reitz -- McIntosh 8 pass to Jones (kick failed) 5:27
Evansville Reitz -- Bell 68 run (Hudson kick) :35
Northview -- Lancaster 23 pass to Bradshaw (Lancaster to Bradshaw) 6:00
Northview -- Baker 2-5, Lancaster 21-32, Sorlie 14-76, Crowder 1-(-2), Hyatt 1-3, Haviland 1-4.
Evansville Reitz -- Bell 14-198, McIntosh 5-64, Dimmett 1-3, Fletcher 1-5, Hudson 1-(-1), Stutsman 2-6, Carnahan 1-2, C. Dimmett 1-19, Boyl 1-1, Banks 2-4.
Northview -- Lancaster 12-23, 113 yds., 1 TD, 2 INT.
Evansville Reitz -- McIntosh 9-12, 136 yds., 2 TD, 0 INT., Hudson 1-1, 32 yds., 1 TD.
Northview -- Boetjer 4-26, Bradshaw 5-58, Stevenson 1-6, Sorlie 2-13.
Evansville Reitz -- Hudson 3-47, Mahan 1-3, Dimmett 1-43, Carr 1-2, Fletcher 1-6, Jones 3-67.
Next Games -- Evansville Reitz will face Jasper Friday. Northview ended its season 4-6.