Details are limited due to the ongoing investigation. However, Clay County Sheriff Mike Heaton released preliminary information about the ongoing investigation in the accident that occurred around 10:30 a.m.
Heaton indicated investigators believe the accident was caused when a northbound passenger vehicle crossed the double yellow line into southbound traffic, striking a Dodge Big Horn 4X4 edition pick up truck pulling a utility trailer head on.
Due to the severity of the accident, both drivers, who will not be identified until after officials have contacted their families, were trapped inside their vehicles.
At the scene, Heaton said the full extent of the victims' injuries was unclear, but both were awake and taking with medical personnel before being transported.
The female driver of the passenger vehicle was airlifted from the scene to a hospital in Indianapolis by Air Evac, while the male driver of the truck was transported by TransCare Ambulance to Terre Haute Union Hospital.
The road was reopened to traffic around 12:30 p.m.
Members of Brazil City Fire Department, Clay County Search and Rescue and Dick Johnson Volunteer Fire Department responded to the scene.
This story will be updated as further details are released.