The honor was presented during the college's Honors and Awards ceremony.
Krisenko, daughter of Tatyana Sampson, earned a bachelor's degree in applied biology from Rose-Hulman in May.
The Northview High School graduate is now enrolled in graduate school at Purdue University.
The Outstanding Biology Graduate award is based on scholastic achievement, character and potential for future achievement in the field of biology.
At Rose-Hulman, Krisenko was active in the Student Government Association, Student Alumni Association and Chi Omega sorority.
She helped organize the college's Best Buddies program, which matched students with nearby youths with special needs.
She was also one of two Rose-Hulman students nominated for the 2010 All-USA College Academic Team.
Rose-Hulman is the nation's leading undergraduate engineering, mathematics and science college.
For 11 consecutive years, it has been ranked in the annual U.S. News & World Report survey of higher education as the top college or university that offers the bachelor's or master's degree as its top degree in engineering.
Located in Terre Haute, Rose-Hulman offers hands-on education that stresses the development of technical and interpersonal skills in an environmental characterized by close, personal attention for every student.